Actor asked assistant to “give me a big shot”

As new documents show, on the day of his untimely death last October, Matthew Perry asked his assistant to “shoot a big load” of him.

The authorities have now filed charges against five people, including three doctors, the so-called ketamine queen Jasveen Sangha and Perry's assistant Kenneth Iwamasa. The investigation has revealed that there were Friends' star died from ketamine.

After a press conference on Thursday, more details about Perry's final days emerged, including illegal ketamine deals worth several thousand dollars over the course of about a month.

Perry had been receiving ketamine treatments from his primary care doctor to treat depression, but wanted to receive more than the prescription allowed. AP News reported unsealed federal documents. He and Iwamasa met with Dr. Salvador Plasencia, a doctor who had obtained ketamine through another doctor, Mark Chavez, on Sept. 30. Iwamasa paid Plasencia $4,500 in cash that same day, and Plasencia showed the assistant how to inject Perry with the drug. Plasencia later told Chavez via text message that the experience “felt like a bad movie.”

Over the next week, Iwamasa injected Perry with ketamine several times, at one point texting Plasencia that he had found “the sweet spot” after some practice. He began buying vials of the drug from Plasencia instead of just giving himself injections. Iwamasa and Plasencia reportedly met several times and exchanged vials for thousands of dollars in cash.

Later that month, Iwamasa obtained more ketamine from Erik Fleming, an acquaintance of Perry's who once directed and produced Scarlett Johansson and Eva Mendes, who starred in his 1999 children's fantasy comedy. My brother the pigand he produced the first season of the reality show The surreal life in 2003.

Fleming then connected Iwamasa with Jasveen Sangha, the so-called Ketamine Queen. Perry and Iwamasa paid $5,500 for 25 vials of her ketamine, which Fleming delivered to Perry's house. The day before that delivery, Perry and Iwamasa paid Plasencia $21,000 for more of the drug, and Perry suffered a seizure while receiving an injection. Iwamasa said Plasencia told Perry, “We're not doing that again.”

Around October 20, Perry received his last legal ketamine treatment, and a woman whose name is redacted in Justice Department records told investigators she believed Perry had been clean for 19 months at that point.

On October 28, the day of Perry's death, Iwamasa injected Perry at 8:30 a.m., at 12:45 p.m. and one final time at 1:30 p.m. Iwamasa recalled that Perry told him to “give him a big shot” before the final injection. He then left Perry in the hot tub while he ran errands and found the actor facedown in the water when he returned.

When paramedics arrived, they pronounced Perry dead. A later autopsy report listed ketamine as the primary cause of death, with drowning being the second most likely cause.