Cowboys vs. Browns prediction, odds, line, spread, time: 2024 NFL picks, Week 1 best bets from proven model

The NFL's Week 1 schedule features a cross-conference matchup of 2023 playoff teams when the Cleveland Browns host the Dallas Cowboys at Huntington Bank Field. The Cowboys won the NFC East with an overall record of 12-5 but lost to the Green Bay Packers on Wild Card Weekend. The Browns finished 11-6 and also lost in the 2023 Wild Card round. Cleveland leads the all-time series 18-14.

Kickoff is scheduled for 4:25 p.m. ET Sunday at Huntington Bank Field. Cleveland is favored by 2.5 points in the latest Browns vs. Cowboys odds, and the over/under is set at 41.5 points. Before you make your Browns vs. Cowboys picks, you must check out the NFL predictions and betting tips from the proven computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, has gained well over $7,000 in top-rated NFL picks for $100 players since its inception. The model enters Week 1 of the 2024 NFL season with an incredible 181-129 run in top-rated NFL picks dating back to the 2017 season. It also has a 35-21 run in top-rated NFL picks since Week 7 2022. The model has also been in the top 10 in pure NFL picks on NFLPickWatch in four of the last six years and has beaten more than 94% of CBS Sports Football Pick'em players four times during that time period. Anyone who has been following it is way up there.

The model has zeroed in on Browns vs. Cowboys and just locked in its picks and predictions for NFL Week 1. You can head over to SportsLine now to see the model's picks. Here are some NFL odds and betting lines for the game:

• Browns vs. Cowboys spread: Browns -2.5
• Browns vs. Cowboys over/under: 41.5 points
• Browns vs. Cowboys money line: Browns -142, Cowboys +120
• Browns vs. Cowboys Picks: See Picks at SportsLine

Why the Cowboys can cover

The Cowboys have one of the most explosive offenses in the NFL. Quarterback Dak Prescott and wide receiver CeeDee Lamb are perennial Pro Bowl candidates and both are coming off extremely productive seasons in 2023. Prescott threw for 4,516 yards, 36 touchdowns and nine interceptions, while Lamb caught 135 passes for 1,749 yards and 12 touchdowns.

On defense, the Cowboys have the ability to wreak havoc on opposing offenses with their elite pass rush. All-Pro and Defensive Player of the Year candidate Micah Parsons leads Dallas' defense. The three-time All-Pro finished the 2023 season with 64 total tackles, 14.0 sacks, and a forced fumble. Here's which team to choose.

Why the Browns can cover

Statistically, the Browns had the NFL's best defense in 2023. Cleveland allowed a league-leading 270.2 yards per game last season, and they have the majority of that unit back for the 2024 season. Browns DE Myles Garrett is the reigning NFL Defensive Player of the Year and poses a significant challenge to Dallas' offensive line.

Garrett recorded 14 sacks and four forced fumbles in 2023, and Dallas is rebuilding its offensive line and will add a rookie in Tyler Guyton at left tackle. Cleveland also has veterans Shelby Harris, Za'Darius Smith and Dalvin Tomlinson, as well as arguably the best defensive line in the NFL. Here's which team to choose.

How to make your predictions for the Browns vs. Cowboys game

The model has simulated Browns vs. Cowboys 10,000 times and the results are in. The model is trending over on total points and has also generated a point spread pick that is accurate in over 50% of simulations. You can only see the model's picks at SportsLine.

So who will win Browns vs. Cowboys in Week 1 and which side of the spread will win over 50% of the time? Visit SportsLine now to see which side of the Cowboys vs. Browns spread you should bet on, all using the model that has returned well over $7,000 in top-rated NFL picks, and find out.