Christian McCaffrey will not play for the 49ers on Monday night

The 49ers will rely on wide receiver Brandon Aiyuk and left tackle Trent Williams on Monday night against the Jets, but without running back Christian McCaffrey.

McCaffrey said Friday he had no doubts he would play, and head coach Kyle Shanahan and general manager John Lynch also expressed optimism, but McCaffrey's participation is still listed as questionable and is on the team's inactive list. McCaffrey missed most of the summer with a calf injury and is also on the list with an Achilles tendon problem.

Jordan Mason, Patrick Taylor and Isaac Guerendo are the available backs for the Niners.

Also unavailable for the home team are offensive lineman Ben Bartch, quarterback Joshua Dobbs, defensive end Yetur Gross-Matos, safety Talanoa Hufanga, cornerback Darrell Luter and linebacker Dee Winters.

The Jets are missing offensive lineman Max Mitchell, running back Israel Abanikanda, tackle Carter Warren, defensive lineman Leonard Taylor, tight end Brendan Bates, defensive lineman Eric Watts or cornerback Jarrick Bernard-Converse.