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Self-learning AI generates NFL against-the-spread, over-under and money line picks for every game of Week 3, 2024

Steelers vs. Chargers on Sunday will be the first game between 2-0 teams with the two best defenses since 1986. While both are elite on that side of the ball, LA ranks 11th on offense and Pittsburgh ranks just 25th. Still, according to the Week 3 NFL lines, the Steelers are 35-point favorites (2.5 points ahead), with the game having scored a total of 35 points. Both teams are 2-0 ATS and the unders are 2-0 on both teams. But since this matchup has one of the tightest Week 3 NFL spreads, perhaps the right NFL betting tip would be to just bet on the over/under unless you're sure about one side of the spread. Before making any Week 3 NFL picks, you need to look at the NFL against the spread, over/under and moneyline predictions powered by SportsLine AI.

Using cutting-edge artificial intelligence and machine learning techniques, SportsLine's data science team creates AI predictions and AI ratings for each game. The AI ​​predictions are determined by statistical learning from each team's historical data and then quantitatively evaluate the strength of the opponent's defense by assigning a numerical value out of 100, known as the Matchup Score.

Once a prediction is formulated, the AI ​​rating is generated using the prediction, matchup score and the market's odds. For example, you might see an A rating for an Over bet if a team has poor defense, their prediction is off the line and the odds are favorable.

Additionally, SportsLine AI is the first fully automated prediction model at SportsLine. It continually updates itself with the most current data available and can help you spot the biggest discrepancies in the lines. Last season, SportsLine's AI PickBot produced a whopping 1,674 4.5- and 5-star prop picks. Anyone who's been following it is way up there.

For Week 3 NFL betting, AI PickBot has evaluated the NFL odds and provided NFL betting predictions for all 16 games. You can see only the AI ​​predictions for the Week 3 NFL schedule here.

Top AI Picks for Week 3 of the NFL

After analyzing all of the games in Week 3, the AI ​​PickBot says the Rams are 6.5-point underdogs against the 49ers. Since Matthew Stafford joined the Rams in 2021, the team has a 5-2 record against the spread as an underdog at home. The Rams will also return to Los Angeles confident after starting with two consecutive road games, as the team has a 4-0 record in its last four home games, finishing in each of its last three.

Both teams enter this contest banged up, with Puka Nacua, Cooper Kupp, Christian McCaffrey and Deebo Samuel all out. However, given the running and passing abilities of the injured Niners duo, their absences will be felt in both the running and aerial games. LA can still rely on RB Kyren Williams, and he had 100 scrimmage yards with two TDs in his only game against San Fran a year ago. He has scored in both games this season and has a total of 17 touchdowns in his last 14 regular-season games. His presence will help offset injuries to LA's pass receivers, as the AI ​​model has the 49ers (-3.5) winning by less than two points. Check out the other Week 3 predictions and picks at SportsLine.

How to make NFL picks for Week 3

In addition, the AI ​​PickBot has generated five more A-rated picks for Week 3. You must look at the AI ​​PickBot's picks before making any Week 3 NFL bets of your own. You can only see them at SportsLine.

Who will win and cover each Week 3 NFL game, and which A-rated picks should you target? Visit SportsLine now to see the best NFL picks against the spread, over-under and money line, all from the all-new SportsLine AI PickBot, which produced 1,674 top picks last season.