LOOK: Ravens' Derrick Henry scores with a historic TD run against the Bills on Baltimore's first offensive play

Derrick Henry needed just one carry to make history on Sunday night. The star running back led the Baltimore Ravens' first offensive possession of the Week 4 primetime game against the Buffalo Bills and scored an 87-yard touchdown burst, the longest run in franchise history.

Essentially making a single, subtle cutback on the run, Henry easily glided past Bills cornerback Rasul Douglas before outrunning safety Damar Hamlin — and a slew of other Buffalo defenders — on his way to the end zone. His touchdown not only highlighted the nearly 250-pound running back's unteachable physical ability, but it also gave Baltimore an early advantage against Buffalo and gave the Ravens a 7-0 lead.

According to the NFL's Next Gen Stats, Henry reached a top speed of 21.29 mph while running, which was the fourth-fastest speed by a ball carrier this year. He has now reached 20 miles per hour 27 times in his NFL career, trailing only Miami Dolphins wide receiver Tyreek Hill (73).

Sunday night's big score came a week after Henry led the Ravens with 151 yards rushing against the Dallas Cowboys. He entered Week 5 as one of the NFL's top five rushers with 281 yards.