Vanderbilt-Alabama College Football Week 6 Score Prediction

Vanderbilt football returns to FirstBank Stadium on Saturday after three weeks without a home game.

The Commodores (2-2, 0-1 SEC) face a formidable opponent in No. 2 Alabama (4-0, 1-0) in their SEC home opener. The Crimson Tide are coming off a win against Georgia. Vanderbilt didn't have a game last week and previously lost on the road to Missouri in its conference opener.

Entering Saturday (3:15 p.m. CT, SEC Network), the Commodores are on a long losing streak, with 14 straight losses in the series and 24 straight losses using the original result of a retroactively lost game.

Vanderbilt went 55-3 in 2022 and hasn't scored a touchdown against the Crimson Tide since 2007 (the two teams have played just three times since then).