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Biden-Harris administration announces billions in savings through drug price negotiations

In a historic first, the Biden-Harris administration today announced the results of the first round of drug price negotiations made possible by the Inflation Reduction Act (IRA). For 2026, the first year the prices take effect, the administration projects that Medicare beneficiaries will save $1.5 billion in out-of-pocket costs. In total, Medicare is expected to save at least $6 billion in 2026 through the price reductions on 10 drugs. The savings will continue to increase in subsequent years.

The drugs selected for negotiation are associated with high Medicare spending and a lack of competition, among other issues. The resulting list includes drugs relied on by 8.8 million Medicare beneficiaries in 2023 to treat conditions such as cancer, diabetes, blood clots, heart failure, autoimmune diseases and chronic kidney disease.

As requested by the IRA, the government estimated the value of the drugs and set a fairer price rather than simply allowing drug manufacturers to set their prices as they saw fit.

As the following graph shows, the list prices for these drugs are reduced by 38-79%.

Drug name Frequently treated diseases Number of Medicare beneficiaries who used the drug in 2023 Drug list price 2023 for 30-day supply Negotiated price for 2026 for 30-day delivery Savings (%)
Eliquis Prevention and treatment of blood clots 3,928,000 521 $ 231 US dollars 290 USD (-56%)
Jardiance Diabetes; Heart failure; Chronic kidney disease 1,883,000 573 $ 197$ 376 USD (-66%)
Xarelto Prevention and treatment of blood clots; risk reduction for patients with coronary or peripheral arterial disease 1,324,000 517 $ 197$ 320 USD (-62%)
Januvia diabetes 843,000 $527 113 $ 414 USD (-79%)
Farxiga Diabetes; Heart failure; Chronic kidney disease 994,000 556 $ $178.50 $377.50 (-68%)
Entry Heart failure 664,000 $628 $295 333 USD (-53%)
Enbrel Rheumatoid arthritis; Psoriasis; Psoriatic arthritis 48,000 $7,106 $2,355 4,751 USD (-67%)
Imbruvica Blood cancer 17,000 14,934 USD 9,319 USD 5,615 USD (-38%)
Stelara Psoriasis; psoriatic arthritis; Crohn's disease; ulcerative colitis 23,000 13,836 USD 4,695 USD 9,141 USD (-66%)
fiasp; Fiasp FlexTouch; Fiasp PenFill;
NovoLog; NovoLog FlexPen; NovoLog PenFill
diabetes 785,000 $495 119$ 376 USD (-76%)
Source: CMS,

More drugs will be selected for negotiation in the coming years. The next 15 drugs to be negotiated will be announced later this year.

At Medicare Rights, we welcome this milestone that will curb rising drug prices and help older people afford their medicines while reducing costs to taxpayers. The impact of these negotiations will grow each year as more drugs are offered at prices that better reflect their value.

Read the announcement and information sheet.

Read more about the negotiated prices.

Read more about IRA provisions.