Odds, tips and predictions for Cleveland Guardians at Chicago White Sox

The Cleveland Guardian (82-62) and Chicago White Sox (33-112) will play the middle game of a 3-game series on Tuesday. First pitch from Guaranteed Rate Field is scheduled for 7:40 p.m. ET. Let's check out FanDuel Sportsbook's odds around the Guardians vs. White Sox Opportunities and place your best bets with our expert MLB tips and predictions.

Season series: Guardians lead 6-5

The Guardians took a 5-3 victory in the series opener on Monday. Cleveland took a 5-0 lead after 5 innings, while Chicago scored 3 runs in the bottom of the 7th and 8th innings to make it exciting, but the Guards held on to the run line (-1.5, -140).

The White Sox have been awful all season, but especially lately. Since August 23, Chicago has lost 15 of its last 17 games, and 13 of the losses have been by 2 or more runs.

In terms of overall results, Chicago has won by a small margin in 3 of their last 4 games, while the under record is 9-4 in their last 13 games. For Cleveland, the under record is 4-0-1 in their last 5 games and 7-0-2 in their last 9 games.

Guardians at the White Sox: expected starters

RHP Ben Lively against RHP Jonathan Cannon

Lively (11-9, 4.07 ERA) makes his 26th start. He has a WHIP of 1.25, 2.9 BB/9 and 7.2 K/9 in 135 IP.

• Last start: Loss, 4 IP, 4 ER, 7 H (1 HR), 1 BB, 3 K in 4-1 setback against Kansas City Royals last Wednesday
• 2024 Road Splits: 4-7, 4.19 ERA, 68 2/3 IP, 32 ER, 12 HR, 1.27 WHIP, .246 opposing batting average (OBA), 23 BB, 59 K in 13 starts
• Career against White Sox: 1-1, 4.63 ERA, 11 2/3 IP, 6 ER, 1 HR, 1.54 WHIP, 6.2 K/9 in 2 starts

Cannon (3-9, 4.53 ERA) makes his 18th start and 20th appearance. He has a 1.39 WHIP, 2.9 BB/9 and 6.2 K/9 in 101 1/3 IP.

• Last start: Win, 5 2/3 IP, 1 ER, 5 H (1 solo HR), 1 BB, 4 K in the 8-1 road win against the Baltimore Orioles last Wednesday
• 2024 Home Splits: 1-4, 4.17 ERA, 54 IP, 25 ER, 8 HR, 1.31 WHIP, .242 OBA, 21 BB, 36 K in 10 appearances (8 starts)
• Has never faced Guardians

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Guardians at White Sox odds

Provided by FanDuel Sportsbook; for a complete list visit the USA TODAY sports scores and betting odds hub. Odds last updated at 6:36 a.m. ET.

• Moneyline (ML): Guardians -220 (bet $220 to win $100) | White Sox +184 (bet $100 to win $184)
• Running Line (RL)/Against the Spread (ATS): Guardians -1.5 (-142) | White Sox +1.5 (+118)
• Over/Under (O/U): 8.5 (O: -102 | U: -120)

Tips and predictions for the Guardians at the White Sox

forecast

Guardians 4, White Sox 3

Money line

The Guardians (-220) will cost you more than double your potential return against the hapless White Sox (+184). It will be a close game like the series opener on Monday. Cleveland pulled out a narrow 5-3 win, but Chicago didn't give up and scored 3 runs in the late innings against the Guardians' bullpen to make things even more exciting. Expect another close game, as the rookie Cannon hasn't been bad.

HAPPEN.

Running Line/Against the Spread

The WHITE SOX +1.5 (+118) are worth playing with plus money in the middle game on Tuesday.

Chicago has Cannon on the field and he has been pretty consistent at times. The White Sox have won two of their last five games, which is pretty good for them. And against the Guardians, the White Sox are surprisingly competitive at 5-6. Take the ChiSox as underdogs on the run line.

Over/Under

UNDER 8.5 (-120) is the best move on the board

The point total is low at 9-4 in the White Sox's last 13 games, and the point total is low at 7-0-2 in the Guardians' last 9 games. In addition, Under has won in 4 of the last 5 games in the series. Lively and Cannon are also capable of keeping the scores low from the start.

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