Odds, tips and predictions for the game Chicago White Sox vs San Diego Padres

The San Diego Padres (89-66) welcome the Chicago White Sox (36-119) to Petco Park on Sunday for the finale of a 3-game series. First pitch is scheduled for 4:10 p.m. ET. Let's check out BetMGM Sportsbook's MLB odds for the Odds for White Sox vs Padres and place your best bets with our expert MLB tips and predictions.

Season series: Padres lead 2-0

The Padres beat the White Sox 3-2 on Friday to open the series and continued that winning streak with a 6-2 victory on Saturday. They finished both games as clear favorites. They have won 7 of their last 8 games and are in second place in the NL West. San Diego has a 44-36 record at home and a 79-76 record against the spread (ATS) this season.

The White Sox were on a 3-game winning streak from September 14-16, but are now in limbo for 4 games. They lost a 2-1 series to the Los Angeles Angels from Monday through Wednesday. Chicago, despite that winning streak, has lost 8 of its last 11 games. They are 16-61 on the road and 63-92 ATS.

Expected starters for the White Sox at the Padres

RHP Sean Burke against RHP Yu Darvish

Burke (1-0, 2.25 ERA) makes his 2nd start and 3rd appearance. He has a WHIP of 1.38, 3.4 BB/9 and 9.0 K/9 in 8 innings.

• Last start: Win, 5 IP, 2 ER, 5 H, 2 BB, 5 K in the 4-3 home win against Oakland A's on Sunday
• Stats for 2024 with Triple-A Charlotte: 2-6, 4.62 ERA (64 1/3 IP, 33 ER), 1.29 WHIP, 12.0 K/9 in 16 starts
• Has never played against the Padres

Darvish (6-3, 3.21 ERA) is making his 15th start. He has a WHIP of 1.11, 2.4 BB/9 and 8.4 K/9 in 70 innings.

• Last start: Win, 6 IP, 0 ER, 3 H, 2 BB, 3 K in the 3-1 home win against the Houston Astros on Monday
• Home stats 2024: 3-3, 3.75 ERA (48 IP, 20 ER), 1.21 WHIP, 8.3 K/9 in 10 starts
• Career against White Sox: 3-2, 3.57 ERA (45 1/3 IP, 18 ER), 1.30 WHIP, 9.7 K/9 in 7 starts

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Odds for White Sox vs Padres

Provided by BetMGM Sportsbook; visit the USA TODAY Sports Scores and Sports Betting Odds Hub for a complete list of MLB odds. Odds last updated at 9:20 a.m. ET.

• Moneyline (ML): White Sox +280 (bet $100 to win $280) | Padres -350 (bet $350 to win $100)
• Run Line (RL)/Against the Spread: White Sox +2.5 (-130) | Padres -2.5 (+110)
• Over/Under (O/U): 7.5 (O: -120 | U: +100)

Tips and predictions for the White Sox vs. Padres game

forecast

Washington Capitals 1, Pittsburgh Penguins 1

Money line

HAPPEN.

The Padres (-350) are once again the clear favorite in this game, so much so that there is no moneyline bet. The White Sox will probably not be able to avoid a sweep here.

Running Line/Against the Spread

BET PADRES -2.5 (+110).

The Padres have been winning with ease lately, winning a series against the Astros 2-1 Monday through Wednesday and sweeping the San Francisco Giants in three games from Sept. 13-15.

The White Sox have lost 2 of their last 4 games by more than 2 runs. Chicago has scored a total of 7 runs in their last 4 games and will face a strong starting option in Darvish. Expect the Padres to win again by a sizable margin and PADRAS -2.5 (+110).

Over/Under

Bet under 7.5 (+100).

The White Sox have not been able to score consistently lately and have scored under in 3 of their last 4 games. They are 0-3-1 O/U in that stretch. On the season they are 66-80 O/U. Chicago is 3-8-1 O/U in their last 12 games.

The Padres have been under-scored in 5 of their last 6 games (0-5-1 O/U) and have allowed just 4 runs in their last 3 games.

Take UNDER 7.5 (+100).

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